Kristineberg Marine Genomics

Main research interests

Biology of regeneration in brittlestars
(Gene expression – immuno-histology - effect of environmental parameters - functional regeneration - sympatric species - Amphiura filiformis – Amphiura chiajei – runt gene - Echinoderms)

I am currently working on genes expression during arm regeneration in echinoderms and consequences on individual fitness and population

PUBLICATIONS:
MALLEFET J, DEWAEL Y, DUPONT S, PATRUNO & THORNDYKE M (2001) Functional approach of regeneration in Barker M. (ed). Echinoderm 2000. Balkema: Lisse. pp. 301-304.
BRUGGEMAN O, DUPONT S & MALLEFET J (2003) Bioluminescence in the ophiuroid Amphiura filiformis (O.F. Müller, 1776): temperature effects. In Féral JP & David B (eds). Echinoderm Research 2001. Balkema: Lisse. Pp. 177-180.
THORNDYKE M, PATRUNO M, DEWAEL Y, DUPONT S & MALLEFET J (2003) Regeneration in the ophiuroid Amphiura filiformis: cell biology, physiology and luminescence. In Féral JP & David B (eds). Echinoderm Research 2001. Balkema: Lisse. Pp. 193-200.

Micro- and macro-evolution in marine environment
(Intraspecific diversity from genes to behaviour – adaptation and fitness - microevolution - sympatric speciation - exception to the parsimony principle – cosmopolitism - Echinoderms)

I investigate all these aspects using original models such as brittle-stars and original tools such as bioluminescence. This research also leads to the creation of a new genetic marker for bioluminescent animals.

PUBLICATIONS:
DUPONT S (1998) Characterization of bioluminescence variations in an isolated population of Amphipholis squamata (Ophiuroidea, Echinodermata) from Oliveri-Tindari's lagoon (Sicily). Master thesis
DUPONT S (2002) Bioluminescence in Amphipholis squamata: a suitable model for studying microevolution. PhD Thesis.
DUPONT S & MALLEFET J (1999) Population dynamic of Amphipholis squamata (Echinodermata: Ophiuroidea) in Oliveri-Tindari's lagoon system (Sicily). In Candia-Carnevali, MD. & Bonasoro F. (eds). Echinoderm Research 1998. Balkema : Rotterdam. pp. 65-70.
DUPONT S, CHAUFER S, POULIN E, FÉRAL J-P & MALLEFET J (2000) Is there a link between morphological, physiological and genetic variability of the ophiuroid Amphipholis squamata ? Neth. J. Zool.50(3) : 355-363.
DUPONT S & MALLEFET J (2000) Luminous capabilities and life history traits of the polychromatic ophiuroid Amphipholis squamata in two isolated populations from Oliveri-Tindari lagoon system, Sicily. Hydrobiologia. 440 :137-144.
DUPONT S, MALLEFET J & DEWAEL Y (2001) Natural bioluminescence as a genetic marker for ophiuroid species. J. Belg. Zool. 131(2): 19-24.
DUPONT S, VANGELUWE D & MALLEFET J (2001) Arm regeneration in the luminous ophiuroid Amphipholis squamata: a functional approach. In Barker M. (ed). Echinoderm 2000. Balkema: Lisse. pp. 255-259.
FÉRAL J-P, VILLARD A-M., DUPONT S & MALLEFET J (2001) Morphological, physiological and genetic variability of the ophiuroid Amphipholis squamata (Delle Chiaje, 1828) from the lagoon system of Oliveri-Tindari (Sicily). In Barker M. (ed). Echinoderm 2000. Balkema: Lisse. Pp. 261-266.
DUPONT S & MALLEFET J (2002): Abnormal forms in the brittle-star Amphipholis squamata: a field study. J. Mar Biol Ass UK 82: 491-493
DUPONT S (2002). On the taxonomic status of the brittle-star Amphipholis squamata (Delle Chiaje, 1828). Bull. Inst. R. Sc Nat., Biol. 72-S: 105-108.
DUPONT S, SALPIETRO L, COSTANZO M-T & MALLEFET J (2002) Polychromatism and biogeography in the ophiuroid Amphipholis squamata (Delle Chiaje, 1828)(Echinodermata : Ophiuroidea) in the area of Messina (Sicily). Biogeographia XXIII: 193-199.
DUPONT S (2003) Species concept, new techniques and biodiversity crisis: taxonomic status of the cosmopolitan ophiuroid Amphipholis squamata (Delle Chiaje, 1828). In Celnikier LM & Trân Thanh Vân, J (eds) Proceeding of the XIIth Rencontres de Blois, Frontières of life. Thê Gioi Publishers : Vietnam. pp. 83-87.
FAUVILLE G, DUPONT S & MALLEFET J (2003). Bioluminescence in the brittle-star Amphipholis squamata: natural vs. experiment patterns of light emission. In Féral JP & David B (eds). Echinoderm Research 2001. Balkema: Lisse. Pp. 189-192.
DUPONT S, MALLEFET J & VANDERLINDEN C (2004) Effect of beta-adrenergic antagonists on bioluminescence control in three species of brittlestars (Echinodermata: Ophiuroidea). Comp Biochem Physiol C Toxicol Pharmacol. 138(1):59-66.

Data analysis and modelization
(Statistical analysis – qualitative and quantitative data – multivariate analysis – simulation and modelization – genetic analysis)

I have developed expertise in the use of the SAS software. For this reason, I am integrated in diverse researches in very different fields: taxonomy in various groups (insects, molluscs, fish, etc.), genetic psychiatry, psychobiology of the personality, population biology (mites, host/parasitoid system, etc.), etc.

PUBLICATIONS:
DIELEN V, LECOUVET V, DUPONT S & KINET J-M (2001) In vitro regulation of floral transition in tomato (Lycopersicon esculentum Mill.), the model for autonomously flowering plants, using the late flowering uniflora mutant. J. Exp. Botany. 52(357): 715-723.
SALPIETRO L, COSTA F, COSTA M & DUPONT S (2000) A description of mucous channels and cyathiform organs of Buenia affinis Iljin 1930 (Pisces, Gobiidae). Oebalia. XXVI: 109-116.
MASSIN C & DUPONT S (2003). Study on the Leptoconchus (Gastropoda, Coralliophilidae) infesting Fungiidae (Anthozoa: Scleractinia): 1. Presence of nine Operational taxonomic units (OTUs) based on anatomical and ecological characters. Belg. J. Zool. 133(2): 123-128
LEBON O, BASIAUX P, STEEL E, TECCO J, MINNER P, PELC I, VERBANCK P & DUPONT S (2004). Personality profile and drug of choice: a multivariate analysis using Cloninger’s TCI on heroin addicts, alcoholics and a random population group. Drug Alc. Dep. 73: 175-182
DASNOIS L, LEBTAHI K, ABARCA-QUINONES J, HAVAUX N, DUPONT S, DUBOIS V & TROUET A (2004) CPI-0004Na, a new doxorubicin prodrug, reduces growth of 3LL-H61 carcinoma lung metastases in C57BI/6 mice. J Exp. Ther. Oncology. 4: 169-171.
STACH T, DUPONT S, ISRAELSON O, FAUVILLE G, NAKANO H & THORNDYKE M (submitted) Nerve cells of Xenoturbella bocki (phylum uncertain) and Harrimania kupfferi (Enteropneusta) show positive immunoreactivity to antibodies raised against echinoderm neuropeptides. J. Mar. Biol. Ass. UK.

Development of new scientific tools based on Internet technologies
(Scientific publication on Internet – Statistical analysis software – Acquisition of data using modern tools)

I participate to the development of new tools using Internet technologies in order to improve scientific publications and to develop some tools for data acquisitions and analysis.

PUBLICATIONS:
DUPONT S & PIRALI B (2000). SAS helps rapid, transparent dissemination of scientific information, SAS Success Story.
DUPONT S, LEHON M, PIRALI B & ROBERFROID S (2001) CERES, a toolkit to improve scientific diffusion. SAS Belux Academic Newsletter. 3 pages.